(A B12 Status Marker)
(A B12 Status Marker)
The Vitamin B12 test measures a substance called methylmalonic acid (MMA) in the urine, which is a specific indicator of low B12 status. The more MMA you have, the more likely you are to be low in this critical nutrient. View sample report >
Your Vitamin B12 test results are reported in specific units. The units are mmol MMA/mol creatinine (cr). Optimal vitamin B12 status is indicated when the result is below 2.0 mmol MMA/mol cr. A result above 3.8 mmol/mol cr means B12 status is very low and should be confirmed with further testing.
Vitamin B12 is a crucial nutrient responsible for many
functions. Optimal B12 levels have been linked to
Many different conditions, from autoimmune diseases to gut complications, can interrupt B12 absorption. Common medications like proton-pump inhibitors and metformin can also make B12 absorption more difficult. So, often dietary intake is NOT the reason someone has a functional B12 deficiency, which makes testing even more important.
It has been estimated that vitamin B12 deficiency is present in about 20% of the elderly population. Nearly 40% of 3000 subjects in the Framingham Offspring study, were found to be B12 deficient.
Vegans and vegetarians are especially vulnerable to B12 deficiency because it is mainly found naturally in animal foods.
Pregnant women need more B12 to support their baby’s development.
Forty percent of people who take metformin for diabetes have B12 deficiency. This aggravates the neuropathy that is common in diabetes and can lead to serious problems.
People taking antacids or proton pump inhibitors (PPIs) for heartburn can also have B12 deficiency.
People who have had bariatric or other intestinal surgeries are more likely to have issues absorbing B12
Autoimmune diseases can also destroy the parietal cells in the stomach that make intrinsic factor (IF) causing a disease called “pernicious anemia”.
Elderly people can have a digestive system that doesn’t breakdown food as well, which can also contribute to a B12 deficiency.
Supported by science.
B12 levels start changing as soon as you change your diet and lifestyle.
Personalized recommendations based off your test results.
Samples are processed in our CLIA certified laboratory.
Sample analysis traceable to NIST.
Reference ranges show you how you compare to your peers.