Have you ever experienced excruciating leg cramps that wake you up in the middle of the night? You’d know if you had, because leg cramps can be incredibly painful as well as disruptive to your sleep. Not to mention that your vocal pain (e.g., screams), and perhaps a few shock-and-awe words, would have woken up your sleep partner too.

While you’re sleeping isn’t the only time you might experience leg cramps. During exercise is another. Regardless of when your muscles make their move (or rather, refuse to move at all), there are numerous causes for leg cramps, including one which is often overlooked—having certain vitamin or mineral deficiencies.

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The Mayo Clinic defines a muscle cramp as a sudden, unexpected tightening of one or more muscles, adding that they take place mostly in the legs, and even more specifically in the calf, that long stretch of back leg muscle that starts below the knee and ends around your ankle.

Sometimes known as a charley horse (for bizarre reasons having to do with baseball), these stubborn muscle occurrences don’t usually last longer than a few minutes and if you’re lucky just a few seconds. What does a leg cramp feel like? A sudden clenching of the muscle, its malleability replaced by a hard tightening that can cause agonizing pain.


Handling Leg Cramps

What to do? In the immediate, try not to panic or fall out of bed. You can get some relief by rubbing the muscle gently or standing on your legs (if you can), so the muscle cramp will start to stretch out on its own.

The Cleveland Clinic suggests heat, applying a heating pad or a warm bath, or cold, administering an ice pack or ice itself to the area, preferably wrapped in a towel. Then elevate the leg as the cramp pain starts to ease up. Pain medications—ibuprofen or acetaminophen—may also help, but some people have reasons not to take these medications.

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Also, not everyone feels pain the same way, so you may need to find your own method. On the bright side, if your leg cramps come from a nutrient deficiency, there’s potentially an easy way to prevent this kind of muscle pain. Keep reading.

As is often the case with anything health-related, some people are more prone to the condition than others. Here are some potential reasons why you may experience leg cramps:

  • If you exercise too hard, especially if you’re under-conditioned for what you’re trying to do, or you don’t stretch sufficiently, you may find yourself in a muscle tussle.
  • Those with certain medical conditions, such as diabetes, multiple sclerosis, kidney disease, Parkinson’s disease, under- or overactive thyroid, high blood pressure—and these are just some—may experience leg cramps.
  • Pregnancy can bring on muscle cramps, especially if you’re standing on your feet for long periods of time. Oh, the joy!
  • Being overweight may push your muscles beyond where they want to go. Leg cramps are your muscles’ way of showing you they’re in charge.
  • Fatigue and lack of sleep, which is kind of ironic given the fact that leg cramps can interrupt your sleep, thereby making you more tired.
  • Dehydration robs your muscles of the fluids they need to work properly.
  • Not getting enough of certain vitamins (e.g., vitamin B or vitamin D deficiency) or a lack of minerals (e.g., calcium, magnesium, potassium, phosphorous) can be leg cramp drivers. Some emerging research is looking at the potential role for vitamin K in easing leg cramps.
  • Just getting older. Not much you can do about that one except eat right, engage regularly in physical activity, reduce stress and get plenty of sleep. In other words, stay as healthy as you can for as long as you can. That’s your way of showing your muscles that, in fact, you’re in charge.



Vitamin and Mineral Deficiencies May Cause Muscle Cramps

Vitamins and minerals are necessary for your body to function properly. When you’re not getting enough of the vitamins and minerals you need, the results can be devastating.

Here are three vitamin and mineral deficiencies to avoid if you want to eliminate one potential cause of leg cramps:


Vitamin D Deficiency

There’s no question that vitamin D has its figurative hands in several bodily functions and overall good health, from helping build strong bones and teeth to supporting your immune function. There’s also a growing body of evidence that touts other benefits for vitamin D for heart health, cognitive and mood support, and metabolic function.

Further, we know that vitamin D plays a role in muscle health and we’ve blogged before about the growing evidence associating vitamin D deficiency or low levels with chronic and nonspecific musculoskeletal pain, chronic pain, and low back pain as well as muscle weakness, sarcopenia and falls in the elderly.

As to whether a vitamin D deficiency can cause leg cramps, the research is mixed.

For example, one small case series observed the association between vitamin D deficiency and concurrent episodes of pain and muscle spasms. Although the mechanisms are unclear, it’s been hypothesized that the imbalanced homeostasis of electrolytes, including calcium, magnesium, and phosphorus, resulting from vitamin D deficiency, could lead to muscle dysfunction and potential cramping.

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On the other hand, this small study evaluated whether the correction of vitamin D insufficiency relieved muscle cramps in postmenopausal women. The researchers found that vitamin D did not affect the frequency or severity of muscle cramps despite vitamin D repletion. This same study also found no relationship between muscle cramps and dietary or serum magnesium or fluid intake.

Still, some experts consider a lack of vitamin D to be a potential factor in leg cramps.

What is known for sure is this: vitamin D deficiency is a global health concern, with an estimated 1 billion people (adults and children) thought to be vitamin D deficient. And that deficiency is relatively easy to find (by testing) and fix (by adding more vitamin D to your diet through dietary supplements).

There are signs of vitamin D deficiency, including fatigue, muscle weakness, back or joint pain, hair loss, headaches, depression and problems sleeping. However, as you will probably recognize, these symptoms are not specific to only a vitamin D deficiency but can also be a sign of other health problems.

Therefore, testing your vitamin D blood levels is really the best way to learn whether you are lacking in this important vitamin. Your doctor can prescribe a blood draw, taking blood with a small needle inserted in your vein; or you can order an at-home blood test which generally involves a simple finger prick.

Recommendations from the National Institutes of Health recommend starting life with 400 IU daily of vitamin D, rising to 600 IU at one year, eventually rising to 800 IU for adults 71 years and older. Other experts suggest higher amounts.

At OmegaQuant, we think it’s important to determine how much vitamin D is needed based on how much you already have in your blood. Read more here about desirable vitamin D levels and how testing can help you attain that status.

Beyond adding vitamin D supplements as warranted, other ways to increase your vitamin D blood levels include a doctor-prescribed high dose of vitamin D (for a short period of time), adding vitamin D-rich foods (there aren’t a lot of options, but fatty fish like salmon is a good one) to your diet, and/or increasing your sun exposure (in small doses and with proper sunscreen protection).

VIDEO: What is an Optimal Vitamin D Level?


Magnesium Deficiency

Your body needs magnesium for some very basic purposes, including energy production and cellular, nerve and muscle function. In addition, some research also shows benefit in the areas of healthy blood sugar regulation, maintaining healthy bones, supporting healthy blood pressure levels, improving sleep and reducing symptoms of stress and anxiety.

When it comes to your muscles, this article advises that magnesium contributes to flexibility and helps loosen your muscles to help you avoid injuries. Your muscles need magnesium to properly relax, and that’s one reason why a magnesium deficiency may result in leg cramps.

This piece suggests that it’s magnesium’s role in neuromuscular transmission and muscle contraction that leads to the hypothesis by some researchers that a magnesium deficiency may predispose someone to muscle cramps.

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It appears that much of the evidence supporting the theory about magnesium helping with leg cramps is anecdotal, although some [research] has found a correlation between those with magnesium deficiencies and also leg cramps. In addition, there are some scientific studies that have shown benefit for magnesium in this area.

For example, this piece referenced a 2018 randomized, double-blind, placebo-controlled study that showed some promising signs, including a greater reduction of nocturnal leg cramps in the group taking magnesium oxide monohydrate supplements compared to the placebo group.

And this small randomized clinical trial concluded that the mean number of nocturnal leg cramps per week decreased significantly in both the magnesium oxide and placebo groups, albeit with no significant difference between the two.

Some early warning signs of magnesium deficiency include nausea, vomiting, lack of appetite, fatigue, and weakness.

You need more than just symptoms to determine a magnesium deficiency. Fortunately, your doctor may order a blood test to check your magnesium levels.  Other tests may also be conducted, including an electrocardiogram (ECG), a calcium blood test (magnesium works in combination with calcium), a comprehensive metabolic panel, a potassium blood test (magnesium also has synergies with potassium), and a urine magnesium test, according to this post.

Once you know where you stand, you can determine with your doctor whether or not to add a magnesium supplement to your health routine to determine if that simple solution would raise your magnesium levels (as needed) and determine whether the supplement could help with your leg cramps. Note that some people are contraindicated for magnesium supplements due to potential interactions with medications.


Calcium Deficiency

Calcium is best known for building and maintaining strong bones. But the mineral also serves other purposes, like helping your heart, muscles and nerves work properly. A calcium deficiency, also known as hypocalcemia, can have serious long-term consequences, including osteopenia and osteoporosis.

If you’re lacking in calcium, you may not see symptoms early on; therefore, it’s important to be sure you’re getting the recommended amounts of calcium throughout your life, while at the same time, avoiding an overabundance which can lead to other problems.

This fact sheet shares info on the recommended daily amount of calcium based on age and gender, beginning with 200 mg daily at birth.

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According to this article, as your calcium deficiency progresses, different symptoms may appear. For example, with a mild calcium deficiency, you may experience:

  • Muscle cramps, including those in your legs
  • Brittle nails and dry, scaly skin
  • Abnormally (for you) coarse hair

If left untreated (meaning not doing anything to ensure your calcium levels improve), the next level of symptoms include neurologic symptoms such as confusion, memory problems, depression and hallucinations, while severe calcium deficiency results in these kinds of symptoms:

  • Numbness and tingling in the hands, feet, face, lips or tongue
  • Muscle spasms in your throat that make breathing difficult
  • Seizures
  • Heart arrhythmia
  • Congestive heart failure

Routine blood tests ordered by your doctor may reveal mild calcium deficiency and at-home blood tests are also available. When your blood serum calcium concentration is less than 8.8 mg/dL, you are considered to have hypocalcemia; severe hypocalcemia, often considered an emergency, is identified at <7 mg/dL.

Your doctor will determine what other tests are necessary to find the cause of your hypocalcemia, including other blood tests to determine your levels of magnesium, phosphorus, parathyroid hormone and/or vitamin D. An EKG and bone imaging tests may also be warranted.

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Depending what is causing your calcium deficiency, your doctor may recommend one or more of the following:

  • Adding calcium supplements to your diet
  • Prescribing an oral calcium medication
  • Adding a vitamin D supplement to help with calcium absorption
  • Prescribing a synthetic form of parathyroid hormone
  • A calcium gluconate IV
  • A change in your other medications

Bottom line: Testing to see if you are lacking in vitamin D, magnesium, or calcium is the best way to potentially eliminate one potential cause of muscle cramps. If you’re not deficient or insufficient, then almost certainly you can eliminate those nutrients as the cause of your muscle cramps.

And if you are low on any of those nutrients changing your diet or adding a dietary supplement to your daily routine may bring your levels back to sufficiency and potentially help reduce or eliminate your leg cramps. Be sure to talk with your doctor or other healthcare practitioner about your individual situation.

VIDEO: How do you know if you’re getting to a healthy vitamin D level?

These statements have not been evaluated by the Food and Drug Administration. This test is not intended to diagnose, treat, cure, prevent or mitigate any disease. This site does not offer medical advice, and nothing contained herein is intended to establish a doctor/patient relationship. OmegaQuant, LLC is regulated under the Clinical Laboratory improvement Amendments of 1988 (CLIA) and is qualified to perform high complexity clinical testing. The performance characteristics of this test were determined by OmegaQuant, LLC. It has not been cleared or approved by the U.S. Food and Drug Administration.

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